acmgscaler

cranv1.0.0

Variant Effect Calibration to ACMG/AMP Evidence Strength. Provides a function to calibrate variant effect scores against evidence strength categories defined by the American College of Medical Genetics and Genomics (ACMG) and the Association for Molecular Pathology (AMP) guidelines. The method computes likelihood ratios of pathogenicity via kernel density

License MIT + file LICENSE0 versions1 maintainers0 deps81 weekly dl
https://CRAN.R-project.org/package=acmgscaler
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First published · 2025-09-23 10:51:55

Last updated · 2025-09-23T09:50:08+00:00